The first successful human implant of a 3D-printed cornea made from human eye cells cultured in a laboratory has restored a patient’s sight. The North Carolina-based company that developed the cornea described the procedure as a ‘world first’—and a major milestone toward its goal of alleviating the lack of available donor tissue and long wait-times for people seeking transplants. According to Precise Bio, its robotic bio-fabrication approach could potentially turn a single donated cornea into hundreds of lab-grown grafts, at a time when there’s currently only one available for an estimated 70 patients who need one to see.
“This achievement marks a turning point for regenerative ophthalmology—a moment of real hope for millions living with corneal blindness,” Aryeh Batt, Precise Bio’s co-founder and CEO, said in a statement. “For the first time, a corneal implant manufactured entirely in the lab from cultured human corneal cells, rather than direct donor tissue, has been successfully implanted in a patient.” The company said the transplant was performed Oct. 29 in one eye of a patient who was considered legally blind. “This is a game changer. We’ve witnessed a cornea created in the lab, from living human cells, bring sight back to a human being,” said Dr. Michael Mimouni, director of the cornea unit at Rambam Medical Center in Israel, who performed the procedure.
‘And you shall love the LORD your God with all your heart, with all your soul, with all your mind, and with all your strength.’ This is the first commandment. Mark 12:30
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