The first successful human implant of a 3D-printed cornea made from human eye cells cultured in a laboratory has restored a patient’s sight. The North Carolina-based company that developed the cornea described the procedure as a ‘world first’—and a major milestone toward its goal of alleviating the lack of available donor tissue and long wait-times for people seeking transplants. According to Precise Bio, its robotic bio-fabrication approach could potentially turn a single donated cornea into hundreds of lab-grown grafts, at a time when there’s currently only one available for an estimated 70 patients who need one to see.
“This achievement marks a turning point for regenerative ophthalmology—a moment of real hope for millions living with corneal blindness,” Aryeh Batt, Precise Bio’s co-founder and CEO, said in a statement. “For the first time, a corneal implant manufactured entirely in the lab from cultured human corneal cells, rather than direct donor tissue, has been successfully implanted in a patient.” The company said the transplant was performed Oct. 29 in one eye of a patient who was considered legally blind. “This is a game changer. We’ve witnessed a cornea created in the lab, from living human cells, bring sight back to a human being,” said Dr. Michael Mimouni, director of the cornea unit at Rambam Medical Center in Israel, who performed the procedure.
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