New hormone targets same brain region as GLP-1 drugs to fight obesity

a person using the machine

Researchers at the University of Oklahoma have discovered a hormone that appears to reverse obesity in the body. The new study, published in the journal Cell Reports, used mouse models to identify a naturally occurring hormone called FGF21 (fibroblast growth factor 21). The hormone “appears to work by signaling to a brain region involved in metabolism and appetite regulation, the same area targeted by the popular GLP-1 drugs,” according to a university press release.

PEPTIDES MAY SOON BE EASIER TO GET AMID RFK JR.’S PUSH, BUT EXPERTS WARN OF RISKS FGF21 is reportedly already involved in the development of a drug to treat metabolic dysfunction-associated steatohepatitis (MASH), which is a form of fatty liver disease. Lead study author Matthew Potthoff, PhD, a professor of biochemistry and physiology at OU College of Medicine and deputy director of the OU Health Harold Hamm Diabetes Center, said the study showed how the hormone sends “signals” to the lower back region of the brain.

Source: New hormone targets same brain region as GLP-1 drugs to fight obesity | Fox News

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